机构：[1]Department of Paediatric Cardiology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.[2]The Cardiac Development and Early Intervention Unit, West China Institute of Women and Children's Health, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.[3]Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education Chengdu, Sichuan, China.[4]Key Laboratory of Development and Diseases of Women and Children of Sichuan Province, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Kawasaki disease (KD) is a common systemic vasculitis in childhood that can result in damage to multiple body systems. However, prominent gallbladder (GB) enlargement in the acute stage is especially rare. A 5-year-old boy was admitted to the hospital with an 8-day history of a cervical mass, 7-day history of fever, and 5-day history of abdominal pain and rash. The child was diagnosed with KD. After treatment with high-dose intravenous immunoglobulin therapy (2 g/kg), all clinical manifestations were relieved except the abdominal pain. Enhanced computed tomography showed distinct enlargement of the GB, and a congenital choledochal cyst was strongly suspected. After high-dose glucocorticoid treatment, his obviously enlarged GB returned to normal size in the subacute phase. No abnormality was found during 2 years of follow-up. Prominent GB enlargement may emerge in the acute stage of KD. The enlarged GB can return to normal size within the subacute stage by standard treatment for KD. Proper diagnosis, thorough differential diagnosis, and active anti-inflammatory treatment of KD are crucial to avoid surgery.
基金：
The authors disclosed receipt of the following
financial support for the research, authorship,
and/or publication of this article: This work
was supported by the Project of Science and
Technology Department of Sichuan Province
(Nos. 2019YFS0426 and 2021YFS0094) and
the Scientific Research Project of Sichuan
Health and Family Planning Commission (No.
17PJ260).
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2021]版：
大类|4 区医学
小类|4 区医学：研究与实验4 区药学
最新[2023]版：
大类|4 区医学
小类|4 区医学：研究与实验4 区药学
第一作者：
第一作者机构：[1]Department of Paediatric Cardiology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.[2]The Cardiac Development and Early Intervention Unit, West China Institute of Women and Children's Health, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.[3]Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education Chengdu, Sichuan, China.[4]Key Laboratory of Development and Diseases of Women and Children of Sichuan Province, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
通讯作者：
通讯机构：[1]Department of Paediatric Cardiology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.[2]The Cardiac Development and Early Intervention Unit, West China Institute of Women and Children's Health, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.[3]Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education Chengdu, Sichuan, China.[4]Key Laboratory of Development and Diseases of Women and Children of Sichuan Province, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.[*1]Department of Paediatric Cardiology, West China Second University Hospital, Sichuan University, No. 20, 3rd Section, South Renmin Road, Chengdu 610041, China.
推荐引用方式(GB/T 7714)：
Zhao Liang,Hua Yimin,Zhou Kaiyu.Prominent gallbladder enlargement: Kawasaki disease or other congenital or acquired gallbladder disease? A case report[J].The Journal of international medical research.2021,49(9):3000605211041507.doi:10.1177/03000605211041507.
APA：
Zhao Liang,Hua Yimin&Zhou Kaiyu.(2021).Prominent gallbladder enlargement: Kawasaki disease or other congenital or acquired gallbladder disease? A case report.The Journal of international medical research,49,(9)
MLA：
Zhao Liang,et al."Prominent gallbladder enlargement: Kawasaki disease or other congenital or acquired gallbladder disease? A case report".The Journal of international medical research 49..9(2021):3000605211041507
