机构：[1]Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.四川大学华西医院[2]Department of Urology, Minda Hospital of Hubei Minzu University, Enshi 445000, China.
Many studies explored the prognostic value of the modified Glasgow Prognostic Score (mGPS) in urothelial carcinoma (UC), but the results are controversial. This study aimed to quantify the relationship between pretreatment mGPS and survival in patients with UC.A systematic literature search was conducted using Embase, PubMed, and Web of Science to identify eligible studies published before August 2022. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were used to assess the association between pretreatment mGPS and the prognosis of UC.Thirteen eligible studies involving 12,524 patients were included. A high mGPS was significantly associated with poor overall survival (mGPS 1/0: HR = 1.33, 95% CI 1.12-1.58, p = 0.001; mGPS 2/0: HR = 2.02, 95% CI 1.43-2.84, p < 0.0001), progression-free survival (mGPS 1/0: HR = 1.26, 95% CI 1.03-1.53, p = 0.021; mGPS 2/0: HR = 1.76, 95% CI 1.12-2.77, p = 0.013), recurrence-free survival (mGPS 1/0: HR = 1.36, 95% CI 1.18-1.56, p < 0.0001; mGPS 2/0: HR = 1.70, 95% CI 1.44-2.000, p < 0.0001), and cancer-specific survival (mGPS 2/0: HR = 1.81, 95% CI 1.30-2.52, p < 0.0001). A subgroup analysis of OS also yielded similar results.Evidence suggests that high pretreatment mGPS in UC is closely related to poor survival. Pre-treatment mGPS is a powerful independent prognostic factor in patients with UC.
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2022]版：
大类|2 区医学
小类|2 区医学：内科
最新[2023]版：
大类|3 区医学
小类|2 区医学：内科
第一作者：
第一作者机构：[1]Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.[2]Department of Urology, Minda Hospital of Hubei Minzu University, Enshi 445000, China.
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Tan Daqing,Li Jinze,Lin Tianhai,et al.Prognostic Utility of the Modified Glasgow Prognostic Score in Urothelial Carcinoma: Outcomes from a Pooled Analysis[J].Journal of clinical medicine.2022,11(21):doi:10.3390/jcm11216261.
APA：
Tan Daqing,Li Jinze,Lin Tianhai,Tan Ping,Zhang Jiapeng...&Wei Qiang.(2022).Prognostic Utility of the Modified Glasgow Prognostic Score in Urothelial Carcinoma: Outcomes from a Pooled Analysis.Journal of clinical medicine,11,(21)
MLA：
Tan Daqing,et al."Prognostic Utility of the Modified Glasgow Prognostic Score in Urothelial Carcinoma: Outcomes from a Pooled Analysis".Journal of clinical medicine 11..21(2022)
医学