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An update on Becker's nevus: Pathogenesis and treatment

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机构： [1]Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China [2]Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China [3]Laser Research Centre, Faculty of Health Science, University of Johannesburg, Doornfontein, South Africa

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关键词： Becker's nevus clinical characteristics lasers pathological features treatment

摘要：

Becker's nevus (BN) manifests as a hyperpigmented, sometimes hypertrichotic plaque/patch over the chest and shoulder, and it is in the category of benign cutaneous hamartomas. BN has elongation and fusion of the rete ridge, keratotic plugging, sebaceous hyperplasia, smooth muscle hyperplasia, and hyperpigmentation of the basal/suprabasal layer histologically. This article highlights all issues involved in pathogenesis and treatment options of BN. According to current research, postzygotic ACTB mutations induce BN and Becker's nevus syndrome (BNS). Although several therapy strategies were utilized to treat the pigmentary and hypertrichotic aspects of BN, no definitive standard treatment was identified to far, and further research is needed to better educate BN care.© 2022 Wiley Periodicals LLC.

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出版当年[2022]版：

大类 | 4 区医学

小类 | 4 区皮肤病学

最新[2023]版：

大类 | 4 区医学

小类 | 3 区皮肤病学

第一作者：

第一作者机构： [1]Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China [2]Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China

通讯作者：

通讯机构： [1]Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China [2]Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China [*1]Department of Dermatology, West China Hospital of Sichuan University, No. 37 Guoxue Road, Chengdu, Sichuan,610041, China.

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