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Lipid metabolism and cancer.

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机构： [1]Cancer Institute of The Affiliated Hospital of Qingdao University and Qingdao Cancer Institute, Qingdao, China [2]State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, Chengdu, China [3]Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China [4]School of Life Sciences, Tsinghua University, Beijing, China [5]Zhejiang University Cancer Center, Hangzhou, China.

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Dysregulation in lipid metabolism is among the most prominent metabolic alterations in cancer. Cancer cells harness lipid metabolism to obtain energy, components for biological membranes, and signaling molecules needed for proliferation, survival, invasion, metastasis, and response to the tumor microenvironment impact and cancer therapy. Here, we summarize and discuss current knowledge about the advances made in understanding the regulation of lipid metabolism in cancer cells and introduce different approaches that have been clinically used to disrupt lipid metabolism in cancer therapy.© 2020 Bian et al.

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出版当年[2021]版：

大类 | 1 区

医学

小类 | 1 区免疫学 1 区医学：研究与实验

最新[2023]版：

大类 | 1 区

医学

小类 | 1 区免疫学 1 区医学：研究与实验

第一作者：

第一作者机构： [1]Cancer Institute of The Affiliated Hospital of Qingdao University and Qingdao Cancer Institute, Qingdao, China

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通讯作者：

通讯机构： [1]Cancer Institute of The Affiliated Hospital of Qingdao University and Qingdao Cancer Institute, Qingdao, China [3]Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China [4]School of Life Sciences, Tsinghua University, Beijing, China [5]Zhejiang University Cancer Center, Hangzhou, China.

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